021-51111890
购物车（0）
sales@molnova.cn
KW-2450 free base
CAS No. 904899-25-8
KW-2450 free base ( —— )
产品货号. M36254 CAS No. 904899-25-8
KW-2450 free base is an orally bioavailable inhibitor of insulin-like growth factor 1 receptor (IGF-1R) and insulin receptor (IR) tyrosine kinases with potential antineoplastic activity. IGF-1R/IR inhibitor KW-2450 free base selectively binds to and inhibits the activities of IGF-1R and IR, which may result in the inhibition of tumor cell proliferation and the induction of tumor cell apoptosis. IGF-R1 and IR tyrosine kinases, overexpressed in a variety of human cancers, play significant roles in the stimulation of cellular proliferation, oncogenic transformation, and suppression of apoptosis.
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 2MG | ￥7597 | 有现货 |
|
| 5MG | ￥10336 | 有现货 |
|
| 10MG | ￥13970 | 有现货 |
|
| 25MG | ￥20097 | 有现货 |
|
| 50MG | ￥26432 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
-
产品名称KW-2450 free base
-
注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
-
产品简述KW-2450 free base is an orally bioavailable inhibitor of insulin-like growth factor 1 receptor (IGF-1R) and insulin receptor (IR) tyrosine kinases with potential antineoplastic activity. IGF-1R/IR inhibitor KW-2450 free base selectively binds to and inhibits the activities of IGF-1R and IR, which may result in the inhibition of tumor cell proliferation and the induction of tumor cell apoptosis. IGF-R1 and IR tyrosine kinases, overexpressed in a variety of human cancers, play significant roles in the stimulation of cellular proliferation, oncogenic transformation, and suppression of apoptosis.
-
产品描述KW-2450 free base is an orally bioavailable inhibitor of insulin-like growth factor 1 receptor (IGF-1R) and insulin receptor (IR) tyrosine kinases with potential antineoplastic activity. IGF-1R/IR inhibitor KW-2450 free base selectively binds to and inhibits the activities of IGF-1R and IR, which may result in the inhibition of tumor cell proliferation and the induction of tumor cell apoptosis. IGF-R1 and IR tyrosine kinases, overexpressed in a variety of human cancers, play significant roles in the stimulation of cellular proliferation, oncogenic transformation, and suppression of apoptosis.
-
体外实验——
-
体内实验——
-
同义词——
-
通路Angiogenesis
-
靶点IGF-1R
-
受体IGF-1R
-
研究领域——
-
适应症——
化学信息
-
CAS Number904899-25-8
-
分子量515.63
-
分子式C28H29N5O3S
-
纯度>98% (HPLC)
-
溶解度——
-
SMILESC(=C/C1=C(NC(=O)C=2SC=CC2C)C=C(CN3CCN(C(CO)=O)CC3)C=C1)\C=4C=5C(NN4)=CC=CC5
-
化学全称——
运输与储存
-
储存条件(-20℃)
-
运输条件With Ice Pack
-
稳定性≥ 2 years
参考文献
产品手册
关联产品
-
KW-2450 free base
KW-2450 free base is an orally bioavailable inhibitor of insulin-like growth factor 1 receptor (IGF-1R) and insulin receptor (IR) tyrosine kinases with potential antineoplastic activity. IGF-1R/IR inhibitor KW-2450 free base selectively binds to and inhibits the activities of IGF-1R and IR, which may result in the inhibition of tumor cell proliferation and the induction of tumor cell apoptosis. IGF-R1 and IR tyrosine kinases, overexpressed in a variety of human cancers, play significant roles in the stimulation of cellular proliferation, oncogenic transformation, and suppression of apoptosis.
-
HNMPA
HNMPA 是胰岛素受体酪氨酸激酶抑制剂，抑制人胰岛素受体的丝氨酸和酪氨酸自磷酸化。
-
Guvacine ethyl ester...
槟榔碱存在于坚果中。槟榔碱是从槟榔中分离出来的。槟榔碱是一种生物碱天然产物，存在于槟榔（槟榔棕榈（Areca catechu）的果实）中。
